Extraction, partial purification, and antibacterial activity of phycocyanin from Spirulina isolated from fresh water body against various human pathogens
نویسندگان
چکیده
The phycobilin pigments are intensively fluorescence and water soluble. They are categorized into three types: pigments containing high energies (phycoerythrins), intermediate energies (phycocyanins), and low energies (allophycocyanins). Among them, crude-phycocyanin (c-pc) has been considered to be the most preferred one. The present study was undertaken to evaluate the antibacterial activity of c-pc which was isolated from the blue green algae Spirulina platensis. C-pc was extracted by sonication, followed by centrifugation and filtration. The crude form of phycocyanin was purified by ammonium sulphate precipitation, membrane filtration, and dialysis method. Antibacterial activities were obtained from various human pathogens. The results showed that all Spirulina maxima extracts exhibited great potential antibacterial activities against five bacterial strains with inhibition zones of range 7–13 mm.
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Optimization,Purification and characterization of Phycocyanin from Spirulina platensis
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